Article
Hormone Replacement Therapy and Breast Morphology
Hormone replacement therapy (HRT) is used to manage menopausal symptoms and can influence breast morphology. HRT typically involves estrogen, sometimes combined with progesterone or testosterone.
Effects on Breast Tissue
- Estrogen: Restores some lost volume and skin elasticity in postmenopausal women, counteracting atrophy and fat redistribution.
- Progesterone: Supports glandular tissue and ductal structures.
- Testosterone: May be added to improve sexual function but can cause side effects if overdosed.
Risks and Considerations
- HRT may increase the risk of breast cancer, especially with long-term use.
- HRT can affect mammographic density, complicating breast cancer screening.
- The effects of HRT vary based on age, genetics, and hormone dosage.