Cannabidiol (CBD)
Cannabidiol (CBD)
Cannabidiol (CBD) is a non-intoxicating phytocannabinoid found in Cannabis. It has gained attention for potential therapeutic effects and is available in multiple formulations, from prescription medicines to over-the-counter supplements.
Uses
- Medical: Licensed CBD preparations (e.g., Epidiolex) are used for specific epilepsy syndromes. Research continues into anxiety, pain, addiction and other conditions, but high-quality evidence is limited for many claims.
- Wellness products: Oils, capsules, topicals and edibles marketed for general wellbeing, though regulatory oversight varies.
Pharmacology
CBD interacts with multiple molecular targets and can modulate effects of THC. It does not bind strongly to CB1 receptors in the same way THC does.
Safety
- Side effects: Fatigue, gastrointestinal upset, changes in appetite, potential drug interactions (e.g., with medications metabolised by CYP enzymes).
- Regulation: Legal status and product quality vary by jurisdiction; unregulated products may contain variable amounts of CBD and THC.